Ni(II), Pd(II) and Pt(II) complexes with SacNac tridentate ligand

Organometallic and coordination nickel, palladium and platinum complexes, neutral and cationic, with general formula [M(?3-SacNac)X] and [M(?3-SacNac)L?][BPh4] (where M?=?Ni, Pd and Pt, X?=?Me, Cl, 1?6; M?=?Ni, X?=?N3, SMe, 7?8; M?=?Pd, X?=?I, 13; M?=?Ni and Pd, L??=?PPh3, 9?10; M?=?Ni and Pt, X?=?PMe3, dmso, 11?12) containing a new SacNac N,N,S-tridentate ligand [C6H5(S)CCH2C(N-CH2CH2CH2NHC6H5)CH3] were synthetized and obtained as microcrystalline solids. Compounds 2?13 were fully characterized by elemental analysis, IR, 1D and 2D NMR spectroscopy. The structure of the ligand and eight complexes was determined by X-ray crystallographic analysis. The ligand can be both mono- or bi-deprotonated under mild reaction conditions. Results in Heck reaction and antiproliferative activities are reported.