Novel Route to Ynamides: Stable Ligands Equivalent to Unstable Oxazol-4-Ylidenes.
Mendoza Espinosa, Daniel
2012
Ung, G.; Mendoza-Espinosa, D.; Bertrand G. Novel Route to Ynamides: Stable Ligands Equivalent to Unstable Oxazol-4-Ylidenes. Chem. Commun. 2012, 48, 7088-7090.
Abstract
Deprotonation of an oxazolium salt induces a ring opening process leading to the corresponding ynamide. Although the expected mesoionic carbene is not obtained, the acyclic ynamide readily reacts with various transition metals yielding robust mesoionic carbene complexes.
Related articles
Transesterifications mediated by t-BuNH2
Role of lipid peroxidation in biliary obstruction in the rat.
Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives
One-potsynthesis of conformationallyrestrictedspirooxindoles
Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
First Total Synthesis of ()-Flustraminol B
Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor