Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives
Rojas Lima, Susana
2011
Heraclio López-Ruiz, Horacio Briseño-Ortega, Susana Rojas-Lima, Rosa Santilllán, Norberto Farfán. Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives . Tetrahedron Letters 2011, 52, 4308-4312. DOI: http://dx.doi.org/10.1016/j.tetlet.2011.06.039
Abstract
A novel, one-pot, phenylboronic acid catalyzed, cyanide promoted synthesis of 2-(2-hydroxyphenyl)benzoxazoles from salicylaldehydes and o-aminophenols is described. The synthesis is characterized by mild conditions, short reaction times, and simple workup of crystalline, high purity products.
Related articles
A practical access to acyl radicals from acyl hydrazides
Diastereomeric C-glycosyloxanthrones from picramnia antidesma
Stereoselective addition of allylmagnesium chloride to the CN bond of [4.3.0] boron heterobicycles
Bis(acetylsalicylato-j2O,O00)diaquacadmium(II)
Structural studies of spiroarsoranes derived from 2-aminophenols